|
|
UDP-galactose + lactosylceramide <=> globotriosylceramide + H+ + UDP
|
2.4.1.228
lactosylceramide 4-alpha-galactosyltransferase
|
–
|
MK
|
|
BRENDA:
BR44202
KEGG:
R03486;
R05960
MetaCyc:
2.4.1.228-RXN
|
|
|
|
UDP-N-acetyl-D-glucosamine + lactosylceramide <=> N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide + UDP + H+
|
2.4.1.206
lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase
|
–
|
MK
|
|
BRENDA:
BR47518
KEGG:
R04493;
R05971
MetaCyc:
2.4.1.206-RXN
|
|
|
|
CMP-N-acetylneuraminate + lactosylceramide <=> ganglioside_GM3 + CMP + H+
|
2.4.99.9
lactosylceramide alpha-2,3-sialyltransferase
|
–
|
MK
|
|
BRENDA:
BR47567
KEGG:
R03488;
R05937
MetaCyc:
2.4.99.9-RXN
|
|
|
|
UDP-galactose + beta-D-glucosyl-N-acylsphingosine <=> lactosylceramide + H+ + UDP
|
2.4.1.274
glucosylceramide beta-1,4-galactosyltransferase
|
–
|
MK
|
|
BRENDA:
BR49761
KEGG:
R03354;
R06276
MetaCyc:
RXN-12119
|
|
|
|
globotriosylceramide + H2O <=> lactosylceramide + D-galactose
|
3.2.1.22
alpha-galactosidase
3.2.1.47
galactosylgalactosylglucosylceramidase
|
–
–
|
K
|
|
BRENDA:
BR16005
KEGG:
R03618;
R05961
MetaCyc:
3.2.1.47-RXN
|
|
|
|
GalNAc-beta-1,4-Gal-beta-1,4-Glc-beta-1,1-Cer <=> N-acetyl-D-galactosamine + lactosylceramide
|
3.2.1.52
beta-N-acetylhexosaminidase
3.2.1.53
beta-N-acetylgalactosaminidase
|
–
–
|
|
|
BRENDA:
BS417019
KEGG:
R03492;
R06001
SABIO-RK:
3284
|
|
|
|
lactosylceramide + H2O <=> glucosylceramide + D-galactose
|
3.2.1.23
beta-galactosidase
|
–
|
K
|
|
KEGG:
R03355
|
|
|
|
CMP-N-acetylneuraminate + lactosylceramide <=> CMP + alpha-N-Acetylneuraminyl-2,6-beta-galactosyl-1,4-beta-D-glucosylceramide
|
2.4.99.1
beta-galactoside alpha-(2,6)-sialyltransferase
|
–
|
|
|
KEGG:
R03489
|
|
|
|
UDP-N-acetyl-D-galactosamine + lactosylceramide <=> UDP + GalNAc-beta-1,4-Gal-beta-1,4-Glc-beta-1,1-Cer
|
2.4.1.92
(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase
|
–
|
|
|
KEGG:
R03490
|
|
|
|
UDP-N-acetyl-D-galactosamine + lactosylceramide <=> UDP + GalNAc-beta-1,4-Gal-beta-1,4-Glc-beta-1,1-Cer
|
2.4.1.92
(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase
|
–
|
K
|
|
KEGG:
R05938
|
|
|
|
lactosylceramide + H2O <=> glucosylceramide + D-galactose
|
3.2.1.23
beta-galactosidase
|
–
|
|
|
KEGG:
R06099
|
|
|
|
lactosylceramide + CMP-N-acetylneuraminate <=> ganglioside_GM3 + CMP
|
2.4.99.1
beta-galactoside alpha-(2,6)-sialyltransferase
|
–
|
|
|
KEGG:
R06121
|
|
|
|
McOse3Cer + H2O <=> lactosylceramide + D-galactose
|
3.2.1.47
galactosylgalactosylglucosylceramidase
|
–
|
|
|
KEGG:
R06136
|
|
|
|
UDP-galactose + lactosylceramide <=> UDP + iGb3-Cer
|
2.4.1.87
N-acetyllactosaminide 3-alpha-galactosyltransferase
|
–
|
K
|
|
KEGG:
R11320
|
|
|
|
CMP-N-acetylneuraminate + lactosylceramide <=> N-acetyl-alpha-neuraminyl-(2rarr6)-beta-galactosyl-(1rarr4)-beta-D-glucosyl-(1harr1)-ceramide + CMP + H+
|
2.4.99.1
beta-galactoside alpha-(2,6)-sialyltransferase
|
–
|
M
|
|
MetaCyc:
2.4.99.11-RXN
|
|
|
|
UDP-N-acetyl-D-galactosamine + lactosylceramide <=> ganglioside_asialo-GM2 + H+ + UDP
|
2.4.1.92
(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase
|
–
|
M
|
|
MetaCyc:
RXN-18271
|
|
|
|
UDP-galactose + lactosylceramide <=> UDP + alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
|
2.4.1.37
fucosylgalactoside 3-alpha-galactosyltransferase
|
–
|
|
|
BRENDA:
BS421627
|
|
|
|
UDP-galactose + lactosylceramide <=> UDP + globotriaosylceramide
|
2.4.1.228
lactosylceramide 4-alpha-galactosyltransferase
|
–
|
|
|
BRENDA:
BS322507
|
|
|
|
UDP-N-acetyl-D-galactosamine + lactosylceramide <=> UDP + Galabiosylceramide
|
2.4.1.92
(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase
|
–
|
|
|
BRENDA:
BS323120
|
|
|
|
UDP-N-acetyl-D-galactosamine + lactosylceramide <=> UDP-N-acetyl-D-galactosamine + ganglioside_asialo-GM2
|
2.4.1.92
(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase
|
–
|
|
|
BRENDA:
BS443961
|
|
|
|
lactosylceramide + 3''-phosphoadenylylsulfate <=> lactosylceramide_sulfate + adenosine_3'',5''-bisphosphate
|
2.8.2.11
galactosylceramide sulfotransferase
|
–
|
|
|
BRENDA:
BS360171
|
|
|
|
ganglioside_asialo-GM2 + H2O <=> lactosylceramide
|
3.2.1.52
beta-N-acetylhexosaminidase
|
–
|
|
|
BRENDA:
BS259876
|
|
|
|
lactosylceramide + H2O <=> beta-D-glucose + galactosylceramide
|
3.2.1.62
glycosylceramidase
|
–
|
|
|
BRENDA:
BS140066
|
|
|
|
CMP-N-acetylneuraminate + lactosylceramide <=> CMP + ganglioside_GM4
|
2.4.99.9
lactosylceramide alpha-2,3-sialyltransferase
|
–
|
|
|
BRENDA:
BS436436
|
|
|
|
CMP-N-acetylneuraminate + lactosylceramide <=> CMP + N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide
|
2.4.99.9
lactosylceramide alpha-2,3-sialyltransferase
|
–
|
|
|
BRENDA:
BS355501
|
|
|
|
CMP-N-acetylneuraminate + lactosylceramide <=> CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-beta-D-glucosylceramide
|
2.4.99.1
beta-galactoside alpha-(2,6)-sialyltransferase
|
–
|
|
|
BRENDA:
BS353857
|
|
|
|
H2O + globotriosylceramide <=> lactosylceramide + alpha-D-galactose
|
3.2.1.22
alpha-galactosidase
3.2.1.49
alpha-N-acetylgalactosaminidase
|
–
–
|
|
|
SABIO-RK:
8753
|
|